ICNApedia - 8. Botulinum Toxin

Article Index

8. Botulinum Toxin
Botulinum Toxin Type A Distinct “Acceptor” and Intracellular Site of Action
Botulinum Toxin Type A Mechanism Current Hypothesis
BTX: Use in Cerebral Palsy
BTX: Use in Cerebral Palsy (cont)
BTX: Available Preparations
BOTOX®: Resistance
BOTOX®: Preparation
BOTOX®: Dilution and Reconstitution
BOTOX®: Dosage
BOTOX®: Dose Modifiers
BTX: Lower Limb Pattern and Potential Targets
BTX: Upper Limb Pattern and Potential Targets
BTX: Potential Adverse Effects
Comparison of Phenol and BOTOX®
Combination Therapy: Neurolytics and Chemodenervation
All Pages

Page 12 of 16

115-158

Patterns of spasticity of the lower limb and target muscles in patients with cerebral palsy that can be successfully treated with BTX include the following:

Flexed hip
Flexed knee
Adducted thighs
Stiff (extended) knee
Equinovarus foot
Striatal toe (hitchhiker’s toe)

Russman BS, Tilton A, Gormley ME Jr. Cerebral palsy: a rational approach to a treatment protocol, and the role of botulinum toxin in treatment. Muscle Nerve 1997;20 (suppl 6):S181-93.