Complications of ITB can be local or systemic. Local complications include the accumulation of serous fluid or blood at the surgical site, erosion of the pump through the skin or infection. Systemic complications include drug withdrawal (eg, increased spasticity, hallucinations, seizures) or drug toxicity (eg, drowsiness, dizziness, somnolence, respiratory depression, coma).

Other potential complications include meningitis, urinary retention/constipation and possible progression of scoliosis. Complications specifically related to the catheter can also occur. These include migration of the catheter, interruption of the flow of baclofen from the reservoir due to breakage, puncture/rupture, dislodgment or disconnection.

In addition, leaks of cerebrospinal fluid may occur.

Kamensek J. Continuous intrathecal baclofen infusions: an introduction and overview. Axone 1999;20:67-72. 

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