HIE prognosis: can we predict using early neurological examination and blood-based biomarkers?

ICNC2024
Symposia: Understanding Prognosis In Neonates With Hypoxic-Ischemic Encephalopathy

HIE prognosis: can we predict using early neurological examination and blood-based biomarkers?
Diedre Murray

Predicting prognosis remains challenging, especially in mild and moderate HIE. This talk will cover current knowledge regarding the utility of early neurological examination and blood-based biomarkers for the prediction of motor and cognitive outcome following HIE. There will be a particular focus on predictors which are suitable for use in a low resource setting.

Learning objectives:

• To summarize current evidence on which clinical factors are useful for the prediction of outcome in neonatal HIE
• To summarize current knowledge on the ability of early neurological examination to predict long term outcome in HIE
• To summarize current evidence on the ability of blood-based biomarkers to predict outcome in HIE

Professor Diedre Murray is a Consultant Paediatrician and Chair of the Department of Paediatrics and Child Health, University College Cork. Prof Murray is the Principal Investigator of the Cork BASELINE birth cohort, one of the largest and most detailed mother-child cohorts in Europe. Prof Murray’s research has focused on early brain injury, and the development of new ways to predict and assess neurocognitive outcome in children, particularly after neonatal hypoxic ischaemic encephalopathy.

Other Lectures in this symposium
How advanced technologies can inform HIE prognosis: EEG, MRI, and advanced prediction modeling.
HIE as a Cause of Cerebral Palsy in Low and High Resource Settings
Headlines, Hopes, and Hardships: Building Prognostic Awareness in Families Affected by HIE