Leigh syndrome

T2 weighted images showing evidence of symmetric signal change within the cerebral peduncles where there is involvement of the corticospinal tracts and further signal change centrally, posterior pons but particularly in each inferior olivary nucleus and inferior cerebellar peduncles. There is also involvement of the nuclei of the tractus solitarius bilaterally. (These areas demonstrated restricted diffusion.) There is also some symmetric abnormal signal (which showed restricted diffusion) in the subthalamic nuclei also but no abnormality within either corpus striatum or thalamus. The brain is otherwise structurally normal. Myelination is normal for age at 16 months. The imaging features are highly suggestive of Leigh's Syndrome.