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Evaluation of demographic, clinical, and EEG findings in pediatric patients being followed up on for MIS-C

Objective:The COVID-19 pandemic resulted in the emergence of multisystem inflammatory syndrome (MIS-C) in children. which has been linked to a variety of symptoms. The purpose of this study was to evaluate the electroencephalography (EEG) findings as well as the neurological symptoms and findings of pediatric patients who had been diagnosed with MIS-C. Methods: The study included children aged 1 month to 18 years who had been diagnosed with MIS-C since March 2020. Patients' demographic characteristics, symptoms at admission and EEG findings obtained during follow-up were all recorded. Results: The study included 51 patients, 31 (60.2%) of whom were male and had a mean age of 108 (6-205) months. The severity of MIS-C was classified as follows: mild [n:26 (51%)], moderate [n:22 (43%)], and severe [n:3 (6%)]. Neurological symptoms were reported by 27 (52.9%) of the patients. Admission complaints were given in Table-1. All patients had their EEGs recorded in terms of sleep and wakefulness. An abnormal EEG was found in 7 (13.7%) of the patients (n:2 generalized, n:5 focal paroxysmal activity). Six weeks later, imaging and control EEG were performed on patients with abnormal EEG. On EEG, only one patient showed generalized epileptiform activity, but cranial magnetic resonance imaging was normal and there was no neurological deficit. Four of the seven patients were asymptomatic, while three had headaches. Conclusion: We focused on the neurological findings of COVID-19 and MIS-C syndrome in this study. EEG disturbances can be seen even in asymptomatic patients in the early stages of the disease.
Keywords: EEG, children, COVID-19 pandemic, MIS-C, neurological findings