Page 283 - ILAE_Lectures_2015
P. 283

Table 3. Dosage guidelines for established antiepileptic drugs in adolescents and ad

DRUG              INDICATIONS                              STA

                                                           DOS

CARBAMAZEPINE     Partial and generalised tonic-clonic     200
CLOBAZAM          seizures                                 10 m

                  Partial and generalised seizures

CLONAZEPAM        Myoclonic and generalised tonic-clonic   1 mg
ETHOSUXIMIDE      seizures                                 500

                  Absence seizures

GABAPENTIN        Partial seizures                         300
LAMOTRIGINE                                                25m
PHENOBARBITAL     Partial seizures and generalised tonic-  60 m
                  clonic seizures
PHENYTOIN                                                  200
                  Partial and generalised tonic-clonic,
PRIMIDONE         myoclonic, clonic and tonic seizures     250
                  Status epilepticus

                  Partial and generalised tonic-clonic
                  seizures
                  Status epilepticus

                  Partial and generalised tonic-clonic
                  seizures

SODIUM VALPROATE  All generalised seizures                 500
                  Partial seizures

TIAGABINE         Partial seizures                         51
TOPIRAMATE        Partial and generalised seizures         25 m

VIGABATRIN        Partial seizures                         500

*od or bid with controlled-release formulation
   278   279   280   281   282   283   284   285   286   287   288