Metabolic derangements and Autism
Possible Role for Metabolism in the Pathogenesis of ASD Overview of Metabolism: Metabolism encompasses biochemical processes for: Converting food into energy to power cells Synthesizing cellular components Eliminating waste (López-Otín et al., 2016) Begins with digestion and…
Migraine in childhood
Review of acute and preventative pharmacologic and non-pharmacologic treatment of pediatric migraine, including recent or ongoing clinical trials.
Familial (Autosomal Dominant) Focal Epilepsies
Overview: Temporal lobe epilepsy was traditionally considered an acquired condition. Causes include lesions such as: Hippocampal sclerosis…
Neural tube development
Day 15 Post-Conception (p/c): Formation of the primitive streak of specialized neuroectoderm on the dorsal surface of the embryo. Hensen’s…
Fetal Neurology
Fetal neurology is a specialized branch of medicine that focuses on the study, diagnosis, and management of neurological conditions…
Investigations in Movement Disorders
Infancy (first 2 years of life) Neonatal Prader - Willi syndrome - hypokinesia and limb dystonia - fluorescent in situ…
The First Description of Tay-Sachs Disease by Warren Tay, 1881
In 1881, British ophthalmologist Warren Tay published his groundbreaking observation of a cherry-red spot on the retina of a child suffering from a neurological disorder. This momentous discovery marked the first description of what would later be known as Tay-Sachs disease, a…
