neurolists:differentiating_between_ohtahara_syndrome_early_myoclonic_encephalopathy

Differentiating between Ohtahara syndrome and Early Myoclonic Encephalopathy

Classic differentiation between Ohtahara syndrome and early myoclonic epilepsy
Differentiation between Ohtahara syndrome and early myoclonic epilepsy
Ohtahara Syndrome Early Myoclonic Encephalopathy
EEG pattern Continuous suppression burst Discontinuous pattern, suppression burst not always evident at first, and often more distinct during sleep
Primary seizure type Tonic spasms Myoclonus
Other seizure types Focal motor seizures Hemiconvulsions Generalized tonic-clonic seizures Focal motor seizuresTonic spasms
Major etiology Structural lesions Metabolic abnormalities
Evolution of disease 75% progress to West syndrome, 12% progress to Lennox-Gastaut syndrome Up to 50% develop transient atypical hypsarrhythmia, with subsequent return to the suppression burst pattern

Adapted from: long:23044011

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