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Table 1. Pharmacokinetics of new antiepileptic drugs available in the UK.

Drug             Absorption         Protein binding
                 (bioavailability)  (% bound)
Eslicarbazepine  Rapid absorption   3040
acetate
Levetiracetam    Rapid absorption   <10
                 (95100%)

Lacosamide       Rapid absorption   <15%
Oxcarbazepine                       3540
                 Rapid absorption
Perampanel       (95100%)          <90%
Pregabalin       Rapid absorption   <5
                 Rapid absorption

Retigabine       Rapid absorption   60–80%
Zonisamide       Rapid absorption   40%
   293   294   295   296   297   298   299   300   301   302   303