Objectives Lymphangioma, is an infrequent congenital malformation of the lymphatic and vascular system and is recognized as a benign tumor. Here, we report medical and genetic assessment of a Tunisian child who harbor an inoperable neonatal lymphangioma of the axilla complicated by neurologic conditions. Methods A 22-month-old male child was seen at our genetic counselling for the genetic management of an inoperable lymphangioma of the right axilla. Results The lymphangioma was diagnosed prenatally as a small cyst. At birth, it was initially small and then progressively increasing in size leading to neurologic deficits of the right hemi body (paresis). There was also, a delay in achieving motor milestones, speech and hearing disorders, repeated epileptic crisis leading to a west disease appeared at the age of five months, and an intellectual disability (mental retardation). Imaging of the axilla showed multiple encapsulated vascular malformations. Whereas, cerebral imaging revealed multiples lymphangiomatic cysts that intercommunicate. The notion of hydrocephalus was also reported. The medical history of the parental families showed many disorders like epileptic seizures, aneuploidies, anophtalmia and cancer. Cytogenetic analysis was without abnormalities. Conclusion Most lymphangiomas occur in the cervical and axilla regions and they can coexist with genetic syndromes. This case of disseminated lymphangioma was complicated by neurologic deficits and epileptic crisis.

Nouha Bouayed Abdelmoula
Medical University of Sfax
Tunisia

Balkiss Abdelmoula
Medical University of Sfax
Tunisia