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surgical intervention may be beneficial. Since we are increasingly able to detect epileptogenic
lesions in children and predict patterns of clinical progress, this will without doubt lead to
increasing emphasis on surgery in childhood.

Suggested reading and reference books

Epilepsy: A Comprehensive Textbook, 1st Edition (Ed. J Engel Jr, et al), 1998. Lippincott-Raven, New York.
Epilepsy Surgery, 1st Edition (Ed. HO Luders), 2000. Lippincott Williams and Wilkins, New York.
Surgical Treatment of the Epilepsies, 2nd Edition (Ed. J Engel), 1997. Raven Press, New York.
The Treatment of Epilepsy, 2nd Edition (Ed. S Shorvon et al), 2004. Blackwell Publishing, Massachusetts.

Further reading

AYKUT-BINGOL C, BRONEN RA, KIM JH et al (1998) Surgical outcome in occipital lobe epilepsy: implications for
pathophysiology. Ann Neurol 44(1), 60-69.
BARBARO NM, QUIGG M, BROSHEK DK et al (2009) A multicentre prospective pilot study of gamma knife
radiosurgery for mesial temporal lobe epilepsy: seizure response, adverse events, and verbal memory. Ann Neurol 65(2),
167-175.
DE ALMEIDA AN, WHEATLEY BM, OLIVIER A (2001) Advanced surgical approach for selective
amygdalohippocampectomy through neuronavigation. Neurosurgery 48(2), 456-457.
FISHER R, SALANOVA V, WITT T et al (2010) Electrical stimulation of the anterior nucleus of thalamus for treatment
of refractory epilepsy. Epilepsia 51(5), 899-908.
LI LM, CENDES F, ANDERMANN F et al (1999) Surgical outcome in patients with epilepsy and dual pathology. Brain
122 (Pt 5), 799-805.
McINERNEY J, ROBERTS DW (2000) Frameless stereotaxy of the brain. Mt Sinai J Med 67(4), 300-310.
McINERNEY J, SIEGEL AM, NORDGREN RE et al (1999) Long-term seizure outcome following corpus callosotomy
in children. Stereotact Funct Neurosurg 73(1-4),79-83.
MOLYNEUX PD, BARKER RA, THOM M et al (1998) Successful treatment of intractable epilepsia partialis continua
with multiple subpial transections. J Neurol Neurosurg Psychiatry 65(1), 137-138.
MULLIGAN LP, SPENCER DD, SPENCER SS (2001) Multiple subpial transections: the Yale experience. Epilepsia
42(2), 226-229.
NEVILLE BG, HARKNESS WF, CROSS JH et al (1997) Surgical treatment of severe autistic regression in childhood
epilepsy. Pediatr Neurol 16(2), 137-140.
OLIVIER A, BOLING W Jr (2000) Surgery of parietal and occipital lobe epilepsy. Adv Neurol 84, 533-575.
ROBERTS DW (2000) Technical advances in the surgical treatment of epilepsy. Adv Neurol 84, 643-649.
SIEGEL AM, ROBERTS DW, HARBAUGH RE et al (2000) Pure lesionectomy versus tailored epilepsy surgery in
treatment of cavernous malformations presenting with epilepsy. Neurosurg Rev 23(2), 80-83.
SPENCER SS, SPENCER DD, SASS K et al (1993) Anterior, total, and two-stage corpus callosum section: differential
and incremental seizure responses. Epilepsia 34(3), 561-567.
SPENCER DD, SPENCER SS, MATTSON RH et al (1994) Access to the posterior medial temporal lobe structures in
the surgical treatment of temporal lobe epilepsy. Neurosurgery 15(5), 667-671.
TANAKA T, OLIVIER A, HASHIZUME K et al (1999) Image-guided epilepsy surgery. Neurol Med Chir 39(13), 895-
900.
WENNBERGER, QUESNEY LF, LOZANO A et al (1999) Role of electrocorticography at surgery for lesion-related
frontal lobe epilepsy. Can J Neurol Sci 26(1), 33-39.
WESTERVELD M, SASS KJ, CHELUNE GJ et al (2000) Temporal lobectomy in children: cognitive outcome. J
Neurosurg 92(1), 24-30.
WILLIAMSON PD, FRENCH JA, THADANI VM et al (1993) Characteristics of medial temporal lobe epilepsy: II.
Interictal and ictal scalp electroencephalography, neuropsychological testing, neuroimaging, surgical results, and
pathology. Ann Neurol 34(6), 781-787.