Choice of AED [ICNApedia]

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{{tag>AED epilepsy}}====== Choice of AED ======
^ Choice Antiepileptic Drug (AED)medication in children                                                                                           ^|||
| Seizure type/syndrome                                        | First Line                    | Second Line                  | Drugs to avoid       |
| Focal seizures                                               | CBZ,LTG,OXC,TPM,VPA           | CLB,GBP,LEV,PHT,TGB,ZON,PGN  |                      |
| Generalised Seizures                                         |                               |                              |                      |
| Absence                                                      | ESM,LTG,VPA                   | CLB,CLM,TPM                  | CBZ,GBP,OXC,TGB,VGB  |
| GTC                                                          | CBZ,LTG,VPA,TPM               | CLB,LEV,OXC,ZON              | TGB,VGB              |
| Myoclonic                                                    | VPA,TPM                       | LTG,CLB,CLM,LEV,[[:content:Piracetam]]    | CBZ,GBP,OXC,TGB,VGB  |
| Tonic                                                        | LTG,VPA                       | CLB,CLM,LEV,TPM              | CBZ,OXC              |
| Atonic                                                       | LTG,VPA                       | LEV,TPM,CLB,CLM              | CBZ,OXC,PHT          |
| [[:content:Childhood absence epilepsy]]                                   | ESM,LTG,VPA                   | LEV,TOP                      | CBZ,OXC,PHT,TGB,VGB  |
| [[:content:Juvenile absence epilepsy]]                                    | LTG,VPA                       | LEV,TPM                      | CBZ,OXC,PHT,TGB,VGB  |
| [[:content:Juvenile myoclonic epilepsy]]                                  | LTG,VPA                       | CLB,CLM,TPM,LEV              | CBZ,OXC,PHT,TGB,VGB  |
| BECTS                                                        | CBZ,LTG,OXC,VPA               | LEV,TPM                      |                      |
| BCOS                                                         | CBZ,LTG,OXC,VPA               | LEV,TPM                      |                      |
| [[:content:Infantile spasms]]                                             | VGB,Steroids                  | CLB,CLM,VPA,TPM              | CBZ,OXC              |
| [[content:dravet_syndrome|Dravets]]                                                      | VPA,TPM,CLB,CLM               | LEV,[[:content:Stiripentol]]              | CBZ,LTG,OXC,VGB      |
| [[:content:Lennox-Gastuat Syndrome]]                                      | VPA,LTG,TPM                   | CLB,CLM,ESM,LEV,RUF          | CBZ,OXC              |
| [[:content:Landau-Kleffner syndrome]]                                     | Steroids,LTG,VPA              | LEV,TPM                      | CBZ,OXC              |
| CSWS                                                         | Steroids,CLB,CLM,VPA,LTG,ESM  | LEV,TPM                      | CBZ,OXC,VGB          |
| [[:content:Myoclonic astatic epilepsy]]                                   | CLB,CLM,VPA,TPM               | LEV,LTG                      | CBZ,OXC              |

ESM [[:content:Ethosuximide]]\\
CLB [[:content:Clobazam]]\\
CLM [[:content:Clonazepam]]\\
GBP [[:content:Gabapentin]]\\
LEV [[:content:Levetiracetam]]\\
LTG [[:content:Lamotrigine]]\\
OXC [[:content:Oxcarbazepine]]\\
PGN [[:content:Pregabalin]]\\
PHT [[:content:Phenytoin]]\\
RUF [[:content:Rufinamide]]\\
TGB [[:content:Tiagabine]]\\
TPM [[:content:Topiramate]]\\
VGB [[:content:Vigabatrin]]\\
VPA [[:content:Valproate]]\\
ZON [[:content:Zonisamide]]\\