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| content:vigabatrin [2020/02/23 18:15] – [Dosage and titration] icna | content:vigabatrin [2020/02/23 18:46] – [Adverse drug reactions] icna | ||
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| * the mechanism of vigabatrin-induced visual field defects are probably due to reversible oedema of the myelin in the optic nerves, retinal cone system dysfunction or both. | * the mechanism of vigabatrin-induced visual field defects are probably due to reversible oedema of the myelin in the optic nerves, retinal cone system dysfunction or both. | ||
| * Other ADRs include sedation, dizziness, headache, ataxia, paraesthesiae, | * Other ADRs include sedation, dizziness, headache, ataxia, paraesthesiae, | ||
| - | * there is no evidence of idiosyncratic ADRs. | + | * there is no evidence of idiosyncratic ADRs |
| + | * movement disorders including dystonia, dyskinesia, and hypertonia have been reported in patients treated for infantile spasms. | ||
| ===== Mechanism of action ===== | ===== Mechanism of action ===== | ||