Lewis Sumner syndrome

alias: Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM)

Prevalence: 1-9 / 1 000 000

Age of onset: Variable

Inheritance: Sporadic

Lewis-Sumner syndrome (LSS) is a rare acquired demyelinating polyneuropathy characterized by asymmetrical distal weakness of the upper or lower extremities and motor dysfunction with adult onset. It is considered to be a variant of chronic inflammatory demyelinating polyneuropathy

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