CSF protein reference values

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Reported reference values for CSF total protein (g/L) in infants, children, and adults.
Age	Mean ± SD^[1](range)	Range^[2]	Mean (range)^[3]
Term newborn		0.40–1.20		0.63 (0.32–2.40)	0.90¹⁾(0.20–1.70)
0–1 week	0.77 ± 0.16 (0.45–1.09)		0.47 (0.27–0.65)
1–2 weeks				0.67²⁾(0.52–1.20)
2–3 weeks	0.66 ± 0.16³⁾ (0.51–1.01)	0.20–0.80⁴⁾
3–4 weeks				0.52⁵⁾ (0.26–0.88)
1–2 months				0.48 (0.17–0.63)
2–3 months	0.45 +/- 0.13⁶⁾ (0.24–0.65)
3–6 months	0.29 ± 0.04 (0.23–0.37)	0.15–0.45⁷⁾
6–12 months	0.27 ± 0.07 (0.17–0.35)
1–16 years	0.22 ± 0.05 (0.16–0.31)
b From Soldin et al. (4). c From Klein and Marcy (5)

¹ Age range, newborn to 1week

² Age range, 0 to 2 weeks

³ Age range, 1 to 4 weeks

⁴ Age range: 0 to 4 weeks

⁵ Age range, 2 to 4 weeks

⁶ Age range, 1 to 3 months

⁷ Age range, 1 month to adult

~~AUTHORS:off~~

1. ^a long:6189754

2. ^a Soldin JS, Brugnara C, KC Gunter, JM. Hicks, eds. Pediatric reference ranges, 2nd ed. Washington: AACC Press, 1997:181pp

3. ^a Statz A, Felgenhauer K. Development of the blood-CSF barrier. Develop Med Child Neurol 1983;25:152–61.

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