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content:benign_familial_neonatal_epilepsy [2020/02/15 17:17] – [Electroencephalography] icna | content:benign_familial_neonatal_epilepsy [2020/02/23 20:32] – icna | ||
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====== Benign familial neonatal epilepsy ====== | ====== Benign familial neonatal epilepsy ====== | ||
Benign familial neonatal epilepsy is a rare autosomal dominant epileptic syndrome characterised by frequent brief seizures within the first days of life. | Benign familial neonatal epilepsy is a rare autosomal dominant epileptic syndrome characterised by frequent brief seizures within the first days of life. | ||
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===== Clinical features ===== | ===== Clinical features ===== | ||
* Seizures mainly occur in full-term normal neonates following a normal pregnancy and delivery and without precipitating factors. Seizures are brief, of 1–2 min and may be as frequent as 20–30 per day. | * Seizures mainly occur in full-term normal neonates following a normal pregnancy and delivery and without precipitating factors. Seizures are brief, of 1–2 min and may be as frequent as 20–30 per day. | ||
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===== Electroencephalography ===== | ===== Electroencephalography ===== | ||
<WRAP right> | <WRAP right> | ||
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{{ : | {{ : | ||
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- | * The inter-ictal EEG may be normal, discontinuous, | + | * The inter-ictal EEG may be normal, discontinuous, |
* The apnoea and tonic motor activity corresponds to synchronous and bilateral flattening of 5–19s on the ictal EEG | * The apnoea and tonic motor activity corresponds to synchronous and bilateral flattening of 5–19s on the ictal EEG | ||
* followed by bilateral and often asymmetrical discharges of spikes and sharp waves with a duration of 1–2 min, coinciding with the vocalisations, | * followed by bilateral and often asymmetrical discharges of spikes and sharp waves with a duration of 1–2 min, coinciding with the vocalisations, | ||
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===== References ===== | ===== References ===== | ||
~~REFNOTES~~ | ~~REFNOTES~~ | ||
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