content:anakinra

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content:anakinra [2020/02/14 17:42]
icna created
content:anakinra [2020/02/14 17:51] (current)
icna
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 ====== Anakinra ====== ====== Anakinra ======
 Anakinra is a recombinant human interleukin-1 receptor antagonist (IL-1Ra). It competitively inhibits binding of IL-1α and IL-1β to the IL-1 receptor type 1. Given daily as subcutaneous injection, it has modest but significant anti-inflammatory efficacy in Rheumatoid arthritis and has been proven of particular benefit in autoinflammatory syndromes, where IL-1 seems to play a pivotal role. Anakinra is a recombinant human interleukin-1 receptor antagonist (IL-1Ra). It competitively inhibits binding of IL-1α and IL-1β to the IL-1 receptor type 1. Given daily as subcutaneous injection, it has modest but significant anti-inflammatory efficacy in Rheumatoid arthritis and has been proven of particular benefit in autoinflammatory syndromes, where IL-1 seems to play a pivotal role.
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 +Anakinra has been reported to be useful in refractory seizures in the chronic phase of [[FIRES]][(:​cite:​31168503>​{{pubmed>​long:​31168503}})].
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 +===== References =====
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 +~~REFNOTES~~
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