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--- content:alpha-feto_protein_serum [2020/02/16 20:53] – icna
+++ content:alpha-feto_protein_serum [2020/02/17 19:41] – [Alpha-Feto protein, serum] icna
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 ====== Alpha-Feto protein, serum ======
-<alert type="warning" icon="glyphicon glyphicon-hand-down">This article is a stub. Please help us improve it</alert>
+{{page>:template:stub}}
 {{tag>labtests}}
 ==== Indications ====
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 Increased serum AFP is a biomarker for [[Ataxia Telangiectasia]], [[ataxia-oculomotor apraxia 2]] (AOA2), [[Deoxyguanosine Kinase Deficiency]](DGUOK) deficiency (hepatocerebral form of mtDNA depletion). Measurement of serum AFP is very useful in the diagnostic workup of [[autosomal recessive cerebellar ataxias]] (ARCAs).
-CSF AFP levels in normal infants also decline with gestational age in proportion to levels of AFP in serum[(:cite:PMID10612715>{{pubmed>short:10612715}})][(:cite:15802029>{{pubmed>short:15802029}})].
-  * median 61 kIU/L (5th-95th centile: 2-889 kIU/L) in infants -69 to 31 days old
-  * median 1.2 kIU/L (5th-95th centile: 0.1-12.5 kIU/L) in infants 32 to 110 days old
   * **Classic Ataxia Telangiectasia**
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     * raised serum/csf lactate
-==== References ====
+CSF AFP levels in normal infants also decline with gestational age in proportion to levels of AFP in serum[(:cite:PMID10612715>{{pubmed>short:10612715}})][(:cite:15802029>{{pubmed>short:15802029}})].
-~~REFNOTES~~
+  * median 61 kIU/L (5th-95th centile: 2-889 kIU/L) in infants -69 to 31 days old
+  * median 1.2 kIU/L (5th-95th centile: 0.1-12.5 kIU/L) in infants 32 to 110 days old