ICNA

Impaired functional connectivity in preterm brains

In their research "Impact of preterm birth on structural and functional connectivity in neonates" presented at the Society for Neuroscience (SFN) conference in Chicago, Oct 19, 2015, Cynthia Rogers and her colleagues at Washington University Neonatal Development Research Lab, Washington University School of Medicine in St. Louis have found that key brain networks involved in attention, communication and emotion were weaker in premature infants, suggesting an explanation for why children born pre...
Continue reading
  6026 Hits
ICNA

Erythropoietin for neuroprotection in preterm infants

High-dose erythropoietin (EPO; a hormone) administered within 42 hours of birth to preterm infants was associated with a reduced risk of brain injury, as indicated by magnetic resonance imaging, according to a study in the August 27 issue of JAMA. Premature infants are at risk of developing encephalopathy of prematurity, which is associated with long-term neurodevelopmental delay. Erythropoietin has been shown to be neuroprotective in experimental and retrospective clinical studies. Russia Ha-Vinh Leuchter, M.D., of the University Hospital of Geneva, Switzerland, and colleagues conducted a study in which 495 infants (born from 26 weeks to 31 weeks and 6 days of...
Continue reading
  8983 Hits
ICNA

Risk of brain injury in preterm babies influenced by genetic variants

Risk of brain injury in premature babies is modulated by common variation in genes associated with schizophrenia and fat metabolism, a new study suggests. Study of single nucleotide polymorphisms alongside DTI studies including tract-based spatial statistics and deformation-based morphometry in brains of preterm infants showed that SNP in Armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) gene linked to neuronal migration and schizophrenia and in fatty acid desaturase  (FADS2) gene encoding rate limiting step in endogenous Polyunsaturated Fatty Acid PUFA synthesis and linked to intelligence was associated with white matter abnormalities. ARVCF2 member of the catenin family modulates neural cell-cell adhesion...
Continue reading
  8958 Hits

pleasedonate