Current Status of Developmental Encephalopathies: Rett Syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder, and FOXG1 Disorder

Current Status of Developmental Encephalopathies: Rett Syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder, and FOXG1 Disorder

Hot
 
0.0
 
0.0 (0)
1131 0 2 0 0
Session Type
Symposium
CME Available
Yes
Date
Wednesday 21 October 2020
Time
10:30 AM – 12:30 PM
Chair(s)
Time converter at worldtimebuddy.com

Add this event to your calendar

AppleGoogleOffice 365OutlookOutlook.comYahoo

Course Description

• To understand the recent advances in the developmental encephalopathies, namely, Rett syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder and FOXG1 Disorder through comparison of the important similarities and critical differentiating features of this expanding group of neurodevelopmental disorders;
• To understand the phenotypegenotype relationships that characterize each disorder; and
• To promote the existing and emerging clinical trials that offer the potential for diseasemodifying or curative promise.

Learning Objectives

  1. Understand the recent advances in the developmental encephalopathies, namely, Rett syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder and FOXG1 Disorder through comparison of the important similarities and critical differentiating features of this expanding group of neurodevelopmental disorders including clinical trajectories and phenotype-genotype correlations.
  2. Understand the current strategies and challenges to develop and promote clinical trials that offer the potential for disease-modifying or curative therapeutics. Impact Statements This educational session helped me to identify changes I could make in my practice related to:
  3. Evaluation, diagnosis, and management of these developmental encephalopathies including directing these children to clinical centers focusing on these disorders.
  4. Educating and advocating for parents and other caregivers regarding the therapeutic opportunities available or under development for these developmental encephalopathies.

Organizer:
Alan Percy, MD; University of Alabama at Birmingham, Birmingham, Alabama, USA

Rett Syndrome: Current Status and Therapeutic Considerations
Jeffrey L. Neul, MD, PhD; Vanderbilt Kennedy Center, Nashville, Tennessee, USA

MECP2 Duplication Disorder: Understanding the Developmental Trajectory and Potential Therapies
Sarika U. Peters, PhD; Vanderbilt University Medical Center, Nashville, Tennessee, USA

CDKL5 Deficiency Disorder: Advances in Understanding and Current Therapeutic Approaches
Nadia Bahi-Buisson, MD, PhD; Necker Enfants Malades University Hospital, APHP, Paris, France

Recent Progress in Genotype-Phenotype Correlations in FOXG1 Disorder
Knut Brockmann, MD
Interdisciplinary Pediatric Center for Children with Developmental Disabilities and Severe Chronic Disorders Children’s Hospital
University Medical Center, University of Göttingen, Göttingen, Germany

Comparison of the Core Features of the Developmental Encephalopathies from the Rett Natural History Study
Eric Marsh, MD, PhD; Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA

ATTENDEE REVIEWS

This activity has not been reviewed yet
Already have an account? or Create an account