Building: Bourbon Cataratas Convention Centre, Foz do Iguaçu
Room: Cataratas II
Date: 2014-05-06 03:45 PM – 04:00 PM
Last modified: 2014-02-09
Abstract
Background Large hemispheric strokes have a high risk of fatal cerebral edema and brain herniation also known as “Malignant infarction of the middle cerebral artery” (MIMCA),this is a severe complication of arterial ischemic stroke seen in the adult population. The description of malignant MCA stroke syndrome in the pediatric population is very scarce(1,2).Objectives Describe the most common clinical, radiological and electrographic features associated with malignant MCA syndrome at the Hospital for Sick Children Methods Patients with a diagnosis of arterial ischemic stroke. A retrospective review of the clinical and radiological findings was performed , from a prospectively collected patients throughout the stroke database at the Hospital for Sick Children.Results We identified 117 children carrying the diagnosis of stroke at the Stroke Program at the Hospital for Sick Children in Toronto, ON Canada from January 2005 to September 2012. . Among these, 69 (58%) had MCA territory involvement. We identified 12 (17%) patients that developed malignant MCA syndrome. The mean age was 6.7 years (range from 0.08 to 15). Conclusion Malignant cerebral edema, is a severe complication of infarcts involving the middle cerebral artery territory. These patients have a more severe deficit on presentation and also prolonged seizures . Large territorial infarcts, and proximal artery occlusion is also seen in these patients. The early recognition of these findings, could be helpful for clinicians in order to identify patients at risk.
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References
1. Hofmeijer J, Algra A, Kappelle LJ, van der Worp H, Preditors of Life-threatening brain edema in middle cerebral artery infarction. Cerebrovasc Dis 2008; 25:176-184
2. Smith SE, Kirkham FJ, Deveber G, Millman G, Dirks PB, Wirrell E, Telfeian AEm Sykes K, Barlow K, Ichord R. Outcome following decompressive craniectomy for malignant middle cerebral artery infarction in children. Dev Med Child Neurol 53:29-33