ICNC2018 Abstracts & Symposia Proposals, ICNC 2014

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Prevalence & Risk Factors for neurological disorders in children aged 9-15 years in northern India
Rashmi Kumar, Anupama Bhave, Roli Bhargava, Girdhar Agarwal

Building: Bourbon Cataratas Convention Centre, Foz do Iguaçu
Room: Iguazu I
Date: 2014-05-05 03:30 PM – 03:45 PM
Last modified: 2014-02-09

Abstract


 

 

Objective: To compute prevalence and study risk factors for neurological disorders (ND) – epilepsy, intellectual disability, motor, vision and hearing defects in children aged 9-15 years in the community.

Methods: A new instrument – Lucknow Neurological Screen (LNS) was developed and validated.  This was used in a two stage community survey for NDs in rural and urban areas of Lucknow, India. Screen positives and a random proportion of screen negatives were validated using predefined criteria. Prevalence of different NDs was calculated by weighted proportions. Demographic, socioeconomic and medical risk factors were compared between validated subjects who were positive and negative for ND by univariate and logistic regression analysis. Final etiological diagnoses were recorded.

 

Results:  Of 6431 children screened (mean age (SD) 139.2 (24.3) months; male 3412, female 3019) 221 were positive. 214 screen positives and 251 screen negatives were validated. Combined prevalence of NDs was 31.3 per 1000 children of this age (weighted 95% confidence intervals  16.5, 46.4). The final model for risk factors for ND on logistic regression included older age (p=0.0142), mud house (p <0.001), delayed cry at birth (p=0.0291) and previous head injury (p=0.0354). Wide ranging causes of ND were identified in the community including postpolio paralysis, tuberous sclerosis, Duchennes muscular dystrophy and subacute sclerosing panencephalitis.

 

Conclusions: Prevalence of ND is high in this region. Lower socioeconomic status, perinatal difficulties and head injury are predictors of ND.  These factors are largely modifiable.

 

 

 

 

 

 

 

 

 


Keywords


prevalence, risk factors, neurological disorders, India

References


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