Introduction: Triclofos is the most commonly used oral sedative in children. This study aimed to evaluate the efficacy and safety of oral Triclofos as sedative for children undergoing sleep EEG.

Methods: This observational study was carried out between 1^st October 2013 and 30^th November 2013 at a tertiary care centre in North India. Consecutive children aged 6 months to 5 years referred for sleep EEG evaluation who required triclofos for sedation were enrolled. After informed consent, clinical details were noted as per a pre-designed Proforma. Triclofos was administered orally at 50 mg/kg followed by EEG recording. Details of sedation, EEG recording and adverse effects were then noted.

Results: Sixty-one children were enrolled during the study period. The median age was 24 months (15-36) with 69% males. The mean duration of sleep in preceding 24-hours was 9.5 (2.5). The median sleep-onset latency after triclofos administration was 27.5 minutes (15-45). The median duration of sleep was 90 (35-120). 14 (23%) required second dose of triclofos. The EEG recording of at least 30 minutes was successful in 56 (91.8%) children. Two children (3.3%) had mild adverse effects within 24 hours (1-vomiting, 1-dizziness).

Conclusions: Triclofos is an effective and safe oral sedative for children undergoing EEG.