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Is botulinum toxin (Botox) therapy beneficial in chronic daily headache in children?
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  • Accepted Answer

    Wednesday, May 16 2012, 09:40 PM - #Permalink
    1
    There is considerable published literature on Botulinum Toxin as a potentially effective treatment for Chronic Daily Headache in adults(1,2,3,4). A recent retrospective case note survey done at the Mayo clinic Rochester studied the case records of 10 children aged 11-17 yrs who had received botulinum toxin for chronic migraine, chronic tension-type headache and trochlear neuralgia.Their observations suggested a potential benefit from botulinum toxin type A in pediatric patients with medically intractable chronic daily headache, particularly in those with chronic migraine(5).

    1)Evers S (June 2006).Curr. Opin. Neurol. 19 (3): 310–5. PMID 16702841.
    2)Silberstein S et al. Headache 40 (6): 445–50. PMID 10849039.
    3)Binder WJ et al. Otolaryngol Head Neck Surg 123 (6): 669–76. PMID 11112955.
    4)Binder WJ et al.Semin Cutan Med Surg 20 (2): 93–100. PMID 11474749.
    5)Karman Ahmed BS et al. Pediatric Neurology 43 (5): 316-19.
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