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Immunisation and Dravet syndrome

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What advice should I give regarding immunisation in a child with "Dravet Syndrome"?
Responses (2)
  • Accepted Answer

    Saturday, September 06 2014, 11:26 AM - #Permalink
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    Vaccination should not be withheld from children with SCN1A mutations because we found no evidence that vaccinations before or after disease onset affect outcome.
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    McIntosh AM, McMahon J, Dibbens LM, Iona X, Mulley JC, Scheffer IE, Berkovic SF.
    Lancet Neurol. 2010 Jun;9(6):592-8.


    http://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=Lancet+Neurol[Jour]+AND+9[Volume]+AND+592[page]
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  • Accepted Answer

    Monday, October 22 2012, 11:32 AM - #Permalink
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    There is no contraindication for immunisation in Dravet Syndrome. However precaution must be taken to try and prevent any febrile episode following the immunisation. Some physicians even advise increasing the dose of AEDs at the time.
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