Handbook of Pediatric Electroencephalography by Veena Kander now on ICNApedia VLE


New drug target for Rett syndrome identified

In a paper published on Jan. 4, 2016, in the online Early Edition of the journal Proceedings of the National Academy of Sciences, researchers from Penn State University reports on the discovery of a novel drug target, which could help in the treatment for Rett Syndrome and other forms of autism-spectrum disorders. In this work, the researchers demonstrate that human neurons derived from induced pluripotent stem cells (iPSCs) from patients with Rett syndrome (Rett neurons), show a significant deficit in neuron-specific K+-Cl− cotransporter2 (KCC2) expression, leading to an impaired GABA functional switch from excitation to inhibition. Restoring KCC2 level rescued GABA...
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Charles Kennedy

Charles Kennedy, one of the first child neurologists in the USA, passed away on October 6, 2015 in Maine at the age of 95 following a brief illness. Born in Buffalo, NY, he attended Nichols School and later Deerfield Academy. He graduated from Princeton University with honors in Chemistry in 1942. At Princeton, in addition to preparing for medical school, he was also a member of the choir, glee club and the Princeton Nassoons (an all male a cappella group). He went on to receive his MD degree at the University of Rochester while in the Navy V-12 program. Internship was...
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Etiology remains unknown in recent Acute Flaccid Paralysis cases in North America

There have been nearly 60 cases identified in California from 2012 - 2015 of acute flaccid myelitis, a rare syndrome described as polio-like, with most patients being children and young adults, according to a study in the December 22/29 issue of JAMA. The cause of the condition in these cases remains unknown. With the elimination of wild poliovirus in populations throughout most of the world, the clinical syndrome of acute flaccid paralysis (characterized by weakness or paralysis and reduced muscle tone) due to spinal motor neuron injury has largely disappeared from North America. Despite occasional case reports, the absence of centralized...
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Inviting Bids for ICNC2020

The International Child Neurology Association (ICNA) invites "letter of intent" from interested parties to enter the bidding to host the International Child Neurology Congress in 2020.Bidders are invited to send a “letter of intent” (not more than a short paragraph from the main coordinator or organizing scientific society (not the conference organising team) to the secretary of the ICNA (jo.wilmshurst@uct.ac.za ). The ICNA Executive Board will select bidders who would be invited to submit a full proposal. This would be guided by the previous geographical representation, and capacity of the meeting to  reach the maximum number of physicians and allied professionals interested in child neurology....
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Recurrent strep A infections and autoimmune neuropsychiatric disorder in children:possible new link

Researchers have discovered how immune cells triggered by recurrent Strep A infections enter the brain, causing inflammation that may lead to autoimmune neuropsychiatric disorders in children. The study, performed in mice, found that immune cells reach the brain by traveling along odor-sensing neurons that emerge from the nasal cavity, not by breaching the blood-brain barrier directly. The findings could lead to improved methods for diagnosing, monitoring, and treating these disorders. The study, led by researchers at Columbia University Medical Center (CUMC) and the University of Minnesota, Minneapolis, was published today in the online edition of the Journal of Clinical Investigation. Recurrent...
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4th European Stroke Organisation Conference (ESOC 2018)