Children with epilepsy more likely to have psychiatric symptoms and gender seems to play a role

A newly published report reveals that children with epilepsy are more likely to have psychiatric symptoms, with gender a determining factor in their development. Findings showed that girls had more emotional problems, while boys had more hyperactivity/inattention problems and issues regarding peer relationships. Details of this study in Norwegian children are now available online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.

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HLA-A*3101, in Caucasian patients linked to increased risk of developing reaction to Carbamazepine

Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactionsResearchers have now identified a gene, called HLA-A*3101, in Caucasian patients that increases the risk of developing a reaction to the drug from 5% to 26%. 

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New Way To Detect Epileptic Seizures

Researchers at Concordia University have pioneered a computer-based method to detect epileptic seizures as they occur - a new technique that may open a window on the brain's electrical activity. Their paper, "A Novel Morphology-Based Classifier for Automatic Detection of Epileptic Seizures," presented at the annual meeting of the Engineering in Medicine and Biology Society, documents the very successful application of this new seizure-detection method. 

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FDA: Risk of oral birth defects in children born to mothers taking topiramate

New data suggest that the drug Topamax (topiramate) and its generic versions increase the risk for the birth defects cleft lip and cleft palate in babies born to women who use the medication during pregnancy, the U.S. Food and Drug Administration said today.

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MOMS trial shows great benefit for fetal surgery in myelomeningocele

fetal surgery for myelomeningocoeleThe results of the  landmark major multi-center randomized clinical trial "Management of Myelomeningocele Study (MOMS)" report on fetal surgery for spina bifida has been published in the 9 February issue of the New England Journal of Medicine, NEJM. The results indicate that prenatal surgery for spina bifida has greatly improved benefits over postnatal repair, by reducing the need for shunting and improving motor outcomes.

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