«Risk factors of the stroke in early age children»

Shaanvar Shamansurov, Shakhlo Saidazizova , Ziyodakhon Abduyaminova

Objective: to analyze risk factors of stroke in early age children. Methods: clinical, anamnestic data, patient interview, SPSS analysis. Results: We examined 364 children with stroke outcomes at the age of 0 to 18years. Ischemic stroke (n=143), hemorrhagic stroke (n=138), IS with hemorrhagic transformation (n=83) (Table 1). Stroke was observed in patients of the age 1-3 month, amounted 241/364 (66.2%) of the cohort. For the patients of 0-29 days of life, hemorrhagic stroke was dominated. In all other age groups, ischemic stroke was dominated (Chi-Square = 72.8, p<0.001). Maternal risk factors were: anemia, eclampsia, bleeding during childbirth, placental abruption, pyelonephritis (p=0.005), bacterial infection (p=0.001).The child's risk factors were: neonatal bilirubinopathy, bacterial/viral infections, more influenced in HS (p < 0.001), IS with hemorrhagic transformation (p = 0.001). Coagulopathy was significant for GI (p < 0.001), also caused by vitamin K deficiency (76.6%). In the development of IS hypoxia during childbirth was important (p = 0.05). Bacterial infection was characterized exactly for IS with hemorrhagic transformation. Cytomegalovirus and herpetic infections were typical for HI (compare IS (p=0.012), IS with hemorrhagic transformation (p=0.062)). A greater aggressiveness of CMV was revealed. Conclusions: risk factors of the stroke depends on the geographic area, social environment, human population. In our population, early manifestation of the stroke matter neonatal jaundice (p=0.01), hemorrhagic syndrome (p=0.048) with impaired blood clotting (p=0.001), vitamin K deficiency, infectious factors, arterial dissection, cortical dysgenesis, stigmas from the cardiovascular system. The combination of which creates difficulties in making correct and early diagnosis.
Keywords: early manifestation, stroke, risk factors

Shaanvar Shamansurov
Center of the professional development of medical workers
Uzbekistan

Shakhlo Saidazizova
Center of the professional development of medical workers
Uzbekistan

Ziyodakhon Abduyaminova
Center of the professional development of medical workers
Uzbekistan
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Shakhlo Saidazizova 
Center of the professional development of medical workers Uzbekistan