CLINICAL FEATURES OF PEDIATRIC ACUTE RHABDOMYOLYSIS
Yeliz Kutat, SERKAN KIRIK
Objective: Here we aim to compare the causes, clinical presentation, and prevalence of acute renal failure (ARF) and clinical features in pediatric rhabdomyolysis with the published data for adults. Guidelines for managing pediatric rhabdomyolysis currently do not exist, but our study aims to support literature general approach to diagnosis, acute management, follow-up, and prevention of pediatric acute rhabdmyolisis. Methods: We performed a retrospective chart review to identify patients with creatinine kinase levels of 1000 IU/L who were treated in the pediatric intensive care unit between january 2016 and august 2021. Results: Two hundred twenty one patients met study eligibility (141 male and 80 female), with a median age of 6,5 years. The most common causes of pediatric rhabdomyolysis were infection (31,2%) and trauma (36,2%) in our study. ARF developed in 24.4% of the patients. 37.6% of them had accompanying chronic diseases, epilepsy and cerebral palsy. Nearby third of one the patients (29.1%) had been died. Other patients (70.9%) were discharged. Conclusion: Novel studies on pediatric rhabdomyolysis are limited, and in our study, AKI rates were found to be lower in children compared to adults. We used chloralhydrate in rhabdomyolysis due to dystonia. Case of COVID-19 related extremely rhabdomyolysis treated.
Keywords: pediatric, rhabdomyolysis, creatine kinase, renal failure
Yeliz Kutat
Firat University
Turkey
SERKAN KIRIK
Firat University
Turkey
Objective: Here we aim to compare the causes, clinical presentation, and prevalence of acute renal failure (ARF) and clinical features in pediatric rhabdomyolysis with the published data for adults. Guidelines for managing pediatric rhabdomyolysis currently do not exist, but our study aims to support literature general approach to diagnosis, acute management, follow-up, and prevention of pediatric acute rhabdmyolisis. Methods: We performed a retrospective chart review to identify patients with creatinine kinase levels of 1000 IU/L who were treated in the pediatric intensive care unit between january 2016 and august 2021. Results: Two hundred twenty one patients met study eligibility (141 male and 80 female), with a median age of 6,5 years. The most common causes of pediatric rhabdomyolysis were infection (31,2%) and trauma (36,2%) in our study. ARF developed in 24.4% of the patients. 37.6% of them had accompanying chronic diseases, epilepsy and cerebral palsy. Nearby third of one the patients (29.1%) had been died. Other patients (70.9%) were discharged. Conclusion: Novel studies on pediatric rhabdomyolysis are limited, and in our study, AKI rates were found to be lower in children compared to adults. We used chloralhydrate in rhabdomyolysis due to dystonia. Case of COVID-19 related extremely rhabdomyolysis treated.
Keywords: pediatric, rhabdomyolysis, creatine kinase, renal failure
Yeliz Kutat
Firat University
Turkey
SERKAN KIRIK
Firat University
Turkey
SERKAN KIRIK
Firat University Turkey
Firat University Turkey