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Pyridoxine-dependent epilepsy is a condition that involves seizures beginning in infancy or, in some cases, before birth.
 
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Severe myoclonic epilepsy in infancy (SME) was described by Charlotte Dravet in 1978. In the Revised ILAE classification of epilepsies, the SMEI named "Dravet syndrome" because of the lack of myoclonic seizures in many patients and is considered under Electroclinical syndromes.
 
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Introduction Paediatric EEG Normal Awake 3-12 months 14 months-2years 3-4 years 5-10 years 11-16 years Hyperventilation Normal Drowsiness, Sleep, Arousal Drowsy patterns Burst Drowsy Patterns V Waves Spindles V Waves and Spindles Positive Occipital Sharp Transients of Sleep (POSTS)...
 
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Usually done in peroxisomopathies, but essential for diagnosis of DBP deficiency when plasma studies are normal.
 
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Vigabatrin (γ-vilyl-GABA; 4-amino-hex-5-enoic acid) was a result of a rational approach to design compounds that enhance the effect of the inhibitory neurotransmitter GABA.1-16
 
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Zika virus is a mosquito-borne flavivirus primarily transmitted by Aedes aegypti mosquitoes (Hayes, 2009; CDC, 2016 ) and to a lesser extent by Aedes albopictus mosquitoes. 
 
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Wiki 6579   0
Zonisamide is a synthetic 1,2-benzisoxazole derivative (1,2-benzisoxazole-3-methanesulfonamide).
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