Investigations in Child Neurology 11818 0
Infancy (first 2 years of life) Neonatal Prader - Willi syndrome - hypokinesia and limb dystonia - fluorescent in situ hybridization/multiplex ligation-dependent probe amplification for deletion paternally inherited chromosome 15
Eponymous syndromes 8694 0
Lewis-Sumner syndrome (LSS) is a rare acquired demyelinating polyneuropathy characterized by asymmetrical distal weakness of the upper or lower extremities and motor dysfunction with adult onset. It is considered to be a variant of chronic inflammatory demyelinating polyneuropathy
Comparitive genomic hybridizationHot
Neurogenetics 9234 0
Comparitive genomic hybridization (CGH) or Chromosomal microarray analysis(CMA) is a modern cytogenetic technique for analyzing variations in DNA copy-number. Alteration in DNA copy number is one of the many ways in which modification of gene expression and function occurs. The technology was initially used for studying chromosomal imbalances in solid tumours.
The Normal EEG - AdultsHot
Clinical Neurophysiology 25896 0
Investigations in Child Neurology 42165 0
The cerebrospinal fluid (CSF) is formed by the choroid plexuses within the ventricles, passes into the subarachnoid space around the spinal cord and finally over the surface of the brain, to be absorbed in the arachnoid villi in the sagittal sinus. The composition of the CSF changes during circulation from its creation to its final absorption. For example, the CSF protein is lowest in the lateral ventricles, intermediate in the lumbar subarachnoid space, and highest in the subarachnoid spaces over the surface of the cerebral hemispheres (where it is occasionally sampled in mistake for subdural fluid). Except when there...
Benign (non-familial) neonatal seizures versus Benign familial neonatal seizuresHot
Epilepsy 4479 0
Benign (no-familial) neonatal seizures versus Benign familial neonatal seizures
Paediatric Glasgow Coma ScaleHot
Neurolists 15217 0
Approach to Epileptic EncephalopathiesHot
Tools and Algorithms 21870 0
Algorithm for approach to investigations in Epileptic Encephalopathies - Click here
The Normal EEG in ChildrenHot
Clinical Neurophysiology 109021 0
The electroencephalograms (EEGs) of infants and children are normally characterized by a greater mixture of waveforms and frequencies than is found in adults. The relative predominance of these wave types varies with age. There may be considerable intersubject variability, possibly because of differences in maturation. Several waveforms, such as the initial response to hyperventilation and posterior slow rhythms of youth, may be normally asymmetrical. Moreover, infants and young children tend to become drowsy during the recording, and the electrographic alterations with drowsiness are greater than those with adults.
Symptomatic drugs for migraine management evaluated in placebo-controlled and open clinical trialsHot
Neurolists 5348 0
References Drug Study Design Evidence level Dose Age(years) Number of patients Responders (%) Active drug Responders (%) Placebo p value ...