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75 results - showing 21 - 30
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Neurolists 4518   0
Disease Enzyme Defect and Genetics Onset Early Manifestations Vision and Hearing Somatic Findings Motor Findings Seizures Labs Clinical Course White matter Globoid (Krabbe) leukodystrophy Recessive galactocerebroside β-galactosidase deficiency. Chromosome 14q21–14q31 Infantile form first 6 mo. Late-onset form 2–6 y. Adolescent and adult forms are rare Feeding difficulties Shrill cry ...
 
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Epilepsy 3456   0
  Adverse Drug Reaction Acute Side Effects   Drug Concentration Dependent Idiosyncratic Chronic Side Effects Carbamazepine Diplopia Dizziness Drowsiness Nausea Unsteadiness Lethargy Blood dyscrasias Rash (HLA antigen testing may be relevant to avoid Stevens–Johnson or toxic epidermal necrolysis) ...
 
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Epilepsy 3132   0
AED Dosing and Target Serum Concentrations
 
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Pharmacopoeia 4176   0
Perampanel, a first-in-class, noncompetitive, α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptor antagonist recently approved for the adjunctive treatment of partial seizures in patients 12 years of age and older when other antiepileptic medications have failed. 
 
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Inflammatory disorders 10750   0
Neuromyelitis optica (NMO) is an inflammatory disorder of the central nervous system (CNS) that predominantly affects the optic nerves and spinal cord.
 
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Vascular Disorders of the CNS 3863   0
Childhood stroke is one of the top ten causes of mortality in childhood. A majority of the survivors have neurological and neuropsychological deficits with significant impact on their participation and health related quality of life. WHO stroke definition includes arterial ischaemic stroke (AIS), intracranial haemorrhage (ICH) and cerebral sinovenous thrombosis (CSVT). It is well recognised that childhood stroke is multifactorial and atherosclerosis, the commonest cause of AIS in adults, is extremely rare in childhood. A number of risk factors are described and at least one factor is found in 80% children. Relatively low numbers of stroke in any one...
 
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Investigations in Child Neurology 4410   0
The MRI can be used to meet the dissemination in space requirement if the McDonald criteria for a positive MRI are applied. The MRI must show three of the following four features: (1) nine or more white matter lesions or one gadolinium-enhancing lesion, (2) three or more periventricular lesions, (3) a juxtacortical lesion, (4) an infratentorial lesion. The combination of an abnormal CSF finding and two lesions on the MRI, of which one must be in brain, can also meet the dissemination in space criteria; the CSF must...
 
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Investigations in Child Neurology 4233   0
CT Brain, with contrast is around 85% sensitive for a diagnosis of CVST. If there is doubt MR Venography should be undertaken Negative CT in the context of persistent neurological impairment should prompt further investigation with MRI or, if this proves impossible, repeat CT, as pathologies such as arterial ischaemic stroke become more apparent on CT with time. In Arterial ischaemic stroke (AIS) as well as brain imaging, investigation should include evaluation for thrombophilia (including anticardiolipin antibodies). The history should include enquiry...
 
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Investigations in Child Neurology 5601   0
{tabulizer:include style[gr.alterora.elemental_2_grey.css] id[tab_rKRBVS3i1M]} Nonspecific combinations of epileptic and non-epileptic phenomena Condition Epileptic component Non-epileptic component Investigations ...
 
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Investigations in Child Neurology 9107   1
{tabulizer:include style[gr.alterora.elemental_2_grey.css] id[tab_tEZSovAKYd]} Paroxysmal non-epileptic events Category Condition Clinical features Investigations ...
75 results - showing 21 - 30
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