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Hatice Bektaşa, Haluk Topaloğlua Department of Paediatric Neurology, Hacettepe Children's Hospital, Ankara, 06100, Turkey ‘Nuclear envelopathies’ are a group of diseases resulting essentially from mutations of the genes encoding parts of the inner nuclear membrane (Emerin, MAN1, LAP2, LBR), nuclear lamina (Lamins A and C; Lamins B1) and outer nuclear membrane (Nesprins) [1) with mutations affecting Emerin, Lamins A/C and Nesprins being rarer compared with other nuclear envelope components. All three have independent disease causing properties in humans, nesprins being the third in chronology. As a historical note, the first emerin mutation was identified in...
 
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Wiki ICNAICNA 6934 0
Zika virus is a mosquito-borne flavivirus primarily transmitted by Aedes aegypti mosquitoes (Hayes, 2009; CDC, 2016 ) and to a lesser extent by Aedes albopictus mosquitoes. 
 
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Wiki ICNAICNA 4212 0
see Neonatal seizures
 
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Wiki ICNAICNA 7003 0
The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy.
 
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Wiki AshokAshok 14899 0
Neonatal epileptic seizures occur from birth to the end of the neonatal period.This is the most vulnerable of all the other periods of life for the development of epileptic seizures, particularly in the first 1 or 2 days from birth. Neonatal seizures differ from those of older children and adults. They may be short-lived events lasting for just a few days, but they often signify serious malfunction or damage of the immature brain, and constitute a neurological emergency that demands urgent diagnosis and management. Most neonatal seizures are acute (pro-voked, occasional, reactive) symptomatic seizures caused by an acute illness...
 
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Wiki AshokAshok 7267 0
Zonisamide is a synthetic 1,2-benzisoxazole derivative (1,2-benzisoxazole-3-methanesulfonamide).
 
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Wiki AshokAshok 7483 0
Vigabatrin (γ-vilyl-GABA; 4-amino-hex-5-enoic acid) was a result of a rational approach to design compounds that enhance the effect of the inhibitory neurotransmitter GABA.1-16
 
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Wiki AshokAshok 13594 0
Levetiracetam is a single enantiomer, (S)-α-ethyl-2-oxo-pyrrolidine acetamide. Levetiracetam, licensed in 1999, is probably the best of all the newer AEDs1-7. It is chemically unrelated to any of the other current AEDs.
 
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Wiki AshokAshok 28381 0
Lamotrigine is a 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine of the phenyltriazine class. It was first licensed for clinical practice in 1991. Lamotrigine is one of the best newer AEDs, although there are now concerns for its use in women and myoclonic epilepsies.
 
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Wiki AshokAshok 23764 0
Lacosamide is a functionalized amino acid (R)-2-acetamido-N-benzyl-3-methoxypropionamide. It is one of the latest AEDs to be licensed (at the end of 2008), under the brand name Vimpat.
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pleasedonate