<![CDATA[Confirmed]]> https://www.icnapedia.org/ https://www.icnapedia.org/neuroimages/8791 <![CDATA[Alexander Disease (male, 4 yrs)]]> https://www.icnapedia.org/neuroimages/8791 ]]> Sun, 22 Jan 2017 19:16:18 +0000 8791 2017-01-22 https://www.icnapedia.org/media/reviews/photos/original/1f/70/ce/2017-01-22-19-33-47-97-1485114073.jpg         var folders = ["../radviewer/8791/t2_tra/", "../radviewer/8791/t2w_tse/", "../radviewer/8791/t1_sag/", "../radviewer/8791/dwi/"];         var title = ['AXIAL T2', 'T2w TSE', 'SAG T1', 'DWI']; ]]> Extensive leukodystrophy changes with a predominance in the frontal regions but also extending towards the parietal lobes and external capsules in keeping with Alexander's disease. These areas demonstrate free diffusivity. There is evidence of an optic pathway glioma. . A second lesion is demonstrated in the dorsal medulla. This is slightly exophytic. This lesion is more pronounced on the sagittal T1 weighted imaging but is probably of very similar size on the axial T2 weighted imaging. There is no hydrocephalus.]]> https://www.icnapedia.org/neuroimages/8788 <![CDATA[Right MCA aneurysm (3yr old male)]]> https://www.icnapedia.org/neuroimages/8788 ]]> Sat, 21 Jan 2017 19:36:37 +0000 8788 2017-01-21 https://www.icnapedia.org/media/reviews/photos/original/40/2b/3e/2017-01-21-19-41-54-48-1485028153.jpg         var folders = ["../radviewer/8788/t2_tra/", "../radviewer/8788/dwi/", "../radviewer/8788/mip/", "../radviewer/8788/t2_tra/"];         var title = ['AXIAL T2', 'DWI', 'MIP', 'AXIAL T2']; ]]> There is an aneurysm arising from the proximal right middle cerebral artery. Reduced flow in the right middle cerebral artery is demonstrated on the MRA study. Within the right sylvian fissure there is subarachnoid haemorrhage demonstrated. Overlying the right frontal convexity there is a high T2 intensity subdural effusion. subarachnoid haemorrhage is demonstrated in the left sylvian fissure in addition, and also the anterior interhemispheric fissure and occipital horns, and the 4th ventricle. There is subdural haemorrhage around the right occipital lobe. No abnormality is demonstrated within the brain parenchyma. No subdural haemorrhage is demonstrated around the left cerebral hemisphere or in the posterior fossa. ]]> https://www.icnapedia.org/neuroimages/8787 <![CDATA[Zellwegers syndrome (female, 6yrs)]]> https://www.icnapedia.org/neuroimages/8787 ]]> Sat, 21 Jan 2017 09:52:20 +0000 8787 2017-01-21 https://www.icnapedia.org/media/reviews/photos/original/22/94/b5/2017-01-21-11-20-57-83-1484998103.jpg         var folders = ["../radviewer/8787/t2_sag/", "../radviewer/8787/t1_sag/", "../radviewer/8787/cor_flair/", "../radviewer/8787/t2_sag/"];         var title = ['SAG T2', 'SAG T1', 'COR FLAIR', 'SAG T2']; ]]> Normally formed cerebral hemispheres, brainstem and cerebellum. There is marked delay in myelination within cerebral white matter.  Some myelination is seen in the internal capsules and corpus callosum, but much less than expected for 6 yr of age.  There is no hyperintensity in cerebral white matter to indicate a leukoencephalopathy.  There are no feature of polymicrogyria or germinolytic cysts.  There is very mild prominence of the subarachnoid spaces and cerebral ventricles]]> https://www.icnapedia.org/neuroimages/8772 <![CDATA[Leigh syndrome]]> https://www.icnapedia.org/neuroimages/8772     AXIAL T2 DWI T1 SAG   ]]> Fri, 13 Jan 2017 16:25:43 +0000 8772 2017-01-13 https://www.icnapedia.org/media/reviews/photos/original/4f/e2/40/2017-01-22-19-46-10-96-1485114792.jpg         var folders = ["../radviewer/8772/t2_tra/", "../radviewer/8772/t1_sag/", "../radviewer/8772/dwi/", "../radviewer/8772/t2_tra/"];         var title = ['AXIAL T2', 'SAG T1', 'DWI', 'AXIAL T2']; ]]> T2 weighted images showing evidence of symmetric signal change within the cerebral peduncles where there is involvement of the corticospinal tracts and further signal change centrally, posterior pons but particularly in each inferior olivary nucleus and inferior cerebellar peduncles. There is also involvement of the nuclei of the tractus solitarius bilaterally. (These areas demonstrated restricted diffusion.) There is also some symmetric abnormal signal (which showed restricted diffusion) in the subthalamic nuclei also but no abnormality within either corpus striatum or thalamus. The brain is otherwise structurally normal. Myelination is normal for age at 16 months. The imaging features are highly suggestive of Leigh's Syndrome. ]]>