This study, it was aimed to make an evaluation in the follow-up and treatment of cases with pseudotumor cerebri syndrome (PTC).
Data was collected from 21 centers in Turkey based on retrospective records, patients with pseudotumor cerebri according to Modified Dandy Criteria and followed for at least 3 months between January 2010 and January 2022 were included. Complaints were examined in terms of demographic data, clinical, radiological findings, treatment options, and follow-up.
688 children were diagnosed with PTC, the mean age was 134.1 months at the onset. In a lumbar puncture, the mean opening pressure was 380 mm-H2O. The majority of girls (58.8%) had, 51.6% primary PTC in diagnostic classification. The obesity rate was 36.6%. The most common symptom was headache (78%). 52 cases (%7.7) were asymptomatic. In magnetic resonance imaging %61 was normal, %9.9 globe flattening,% 7.9 optic nerve tortuosity, 6.1% sinus vein stenosis, and 4.2% empty sella. Treatment was applied medically in order acetazolamide (618/688) as the first choice, topiramate (167/688), steroids (49/688), and furosemide (18/688). Surgical treatment applied to 4.3% of patients: Shunt operations 17/30, optic nerve sheath fenestration 11/30. The mean time to remission of symptoms was 53.5 days during a mean15.9 month follow-up period. while the median time to remission for papilledema was 75.5 days. 76.7% of the patients were in remission, and 10.7% of them were reported to be in relapse.
PTC is mostly idiopathic, can recur, and lead to vision loss. Early diagnosis and effective treatment are important to prevent vision loss.
Keywords: headache, papilledema, pseudotumor, obesity, lumbar puncture
Mehmet Canpolat
Erciyes University Faculty of Medicine, Department of Pediatric Neurology
Ayten Güleç
Erciyes University Faculty of Medicine, Department of Pediatric Neurology
Hüseyin Per
Erciyes University Faculty of Medicine, Department of Pediatric Neurology
İlknur Erol
Baskent University Adana Dr. Turgut Noyan Application and Research Center
Sermin Özcan
Marmara University Medical University, Department of Pediatric Neurology
Nihal Yıldız
Karadeniz Technical University Faculty of Medicine, Department of Pediatric Neurology
Cemile Büşra Ölçülü
Ege University Faculty of Medicine, Department of Pediatric Neurology
Nihal Olgaç Dündar
Çetin Okuyaz
Mersin University Faculty of Medicine, Department of Pediatric Neurology
Yasemin Özkale
Baskent University Adana Dr. Turgut Noyan Application and Research Center
Gülcan Akyüz Yücel
Marmara University Medical University, Department of Pediatric Neurology
Elif Acar Arslan
Seda Kanmaz
Ege University Faculty of Medicine, Department of Pediatric Neurology
Pınar Gençpınar
İzmir Katip Celebi University, SBU Tepecik Training and Research Hospital, Department of Pediatric Neurology
Selcan Öztürk
Serdal Güngör
İnönü University Medical University, Department of Pediatric Neurology
Ahmet Sami Güven
Necmettin Erbakan University, Faculty of Medicine Meram, Department of Pediatric Neurology
Betül Kılıç
Medipol University Faculty of Medicine, Department of Pediatric Neurology
Filiz Mıhçı
Ondokuz Mayıs University Faculty of Medicine, Department of Pediatric Neurology
İsmail Hakkı Akbeyaz
Marmara University Medical University, Department of Pediatric Neurology
Merve Öztürk
Kocaeli University Faculty of Medicine, Department of Pediatric Neurology
Mine Çiğdem Senoğlu
Gulhane training and research hospital, Department of Pediatric Neurology
Semra Hız Kurul
Merve Yavuz
Hülya İnce
VM Medical Park Samsun Hospital, Department of Pediatric Neurology
Şeyda Besen
Baskent University Adana Dr. Turgut Noyan Application and Research Center
Gülten Öztürk
Tülay Kamaşak
Karadeniz Technical University Faculty of Medicine, Department of Pediatric Neurology
Hepsen Mine Serin
Ege University Faculty of Medicine, Department of Pediatric Neurology
Müge Baykan
İzmir Katip Celebi University, SBU Tepecik Training and Research Hospital
Meltem Çobanoğulları Direk
Bilge Özgör
İnönü University Medical University, Department of Pediatric Neurology
Burcu Çalışkan
Necmettin Erbakan University, Faculty of Medicine Meram, Department of Pediatric Neurology
Hüseyin Tan
Atatürk University Faculty of Medicine, Department of Pediatric Neurology
Çisil Çerçi Kubur
Celal Bayar University Faculty of Medicine, Department of Pediatric Neurology
Dilara Füsun İçağasıoğlu
Murat Özkale
Yasemin Topçu
Medipol University Faculty of Medicine, Department of Pediatric Neurology
Merve Hilal Dolu
Ondokuz Mayıs University Faculty of Medicine, Department of Pediatric Neurology
Mesut Güngör
Kocaeli University Faculty of Medicine, Department of Pediatric Neurology
Bülent Unay
Gulhane training and research hospital, Department of Pediatric Neurology
Döndü Ülker Üstebay
Dokuz Eylul University Medical University, Department of Pediatric Neurology
Pakize Karaoğlu
İzmir Behçet Uz Children Hospital, Department of Pediatric Neurology
Hakan Gümüş
Erciyes University Faculty of Medicine, Department of Pediatric Neurology
Turkish Pediatric Pseudotumor Cerebri Study Group Collabora Study Group Collaboration
