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«Risk factors of the stroke in early age children»

Objective: to analyze risk factors of stroke in early age children. Methods: clinical, anamnestic data, patient interview, SPSS analysis. Results: We examined 364 children with stroke outcomes at the age of 0 to 18years. Ischemic stroke (n=143), hemorrhagic stroke (n=138), IS with hemorrhagic transformation (n=83) (Table 1). Stroke was observed in patients of the age 1-3 month, amounted 241/364 (66.2%) of the cohort. For the patients of 0-29 days of life, hemorrhagic stroke was dominated. In all other age groups, ischemic stroke was dominated (Chi-Square = 72.8, p<0.001). Maternal risk factors were: anemia, eclampsia, bleeding during childbirth, placental abruption, pyelonephritis (p=0.005), bacterial infection (p=0.001).The child's risk factors were: neonatal bilirubinopathy, bacterial/viral infections, more influenced in HS (p < 0.001), IS with hemorrhagic transformation (p = 0.001). Coagulopathy was significant for GI (p < 0.001), also caused by vitamin K deficiency (76.6%). In the development of IS hypoxia during childbirth was important (p = 0.05). Bacterial infection was characterized exactly for IS with hemorrhagic transformation. Cytomegalovirus and herpetic infections were typical for HI (compare IS (p=0.012), IS with hemorrhagic transformation (p=0.062)). A greater aggressiveness of CMV was revealed. Conclusions: risk factors of the stroke depends on the geographic area, social environment, human population. In our population, early manifestation of the stroke matter neonatal jaundice (p=0.01), hemorrhagic syndrome (p=0.048) with impaired blood clotting (p=0.001), vitamin K deficiency, infectious factors, arterial dissection, cortical dysgenesis, stigmas from the cardiovascular system. The combination of which creates difficulties in making correct and early diagnosis.
Keywords: early manifestation, stroke, risk factors