Editorial commentary on ‘Toolbox of multi-item measures aligning with ICF core sets for children and youth with cerebral palsy’
We all know that choosing the most appropriate test from the wide variety of measures devised to assess function and interventional outcomes in children and young people with cerebral palsy can be confusing for both researchers and busy clinicians alike. Dr Schiariti's group has provided a comprehensive and robust overview of the current English Language options in line with the ICF framework. As part of this process they also, appropriately, highlight the important role of using validated measures to help us collaborate on an international perspective.
Predicting the IQ of young children from early developmental markers
The article presented by Peyre et al., this edition, addresses the extent to which we can predict the IQ of 5–6 year-old children, an age where in many countries children will enter formal education, from early assessments of developmental milestones. The study uses baseline data from a large population-based sample of French children from the EDEN prospective mother–child cohort study1 and presents data from 1100 children assessed at follow-up aged 5–6 years. The authors use developmental questionnaires completed by parent/carer at 6, 8, 12 and 24 months and use a predictive validity coefficient model to look at correlations with subsequent IQ.
As the first Professor of Paediatric Neurology in the UK appointed in 1989, and subsequently the first Professor of Childhood Epilepsy, Brian Neville made a significant contribution to the understanding and care of neurological disease in childhood around the world.
How might a genetic diagnosis benefit children with dystonia?
Dystonia is a common presentation to the paediatric neurology clinic, and can be caused by a broad range of disease processes and disorders of brain development, much like the childhood epilepsies. Childhood dystonia is most commonly a symptomatic condition, arising due to damage to the developing motor system, e.g. as a consequence of hypoxic ischaemic encephalopathy.1 For a subset of children, dystonia arises as an isolated disorder, with no sign of structural abnormality on conventional magnetic resonance neuroimaging.
Long-term outcome of patients with X-linked adrenoleukodystrophy: A retrospective cohort study
X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder associated with leukodystrophy, myeloneuropathy and adrenocortical insufficiency. We performed a retrospective cohort study to evaluate long-term outcome of patients with X-ALD.